Search results for " Sleep-disordered breathing"

showing 3 items of 3 documents

Twenty-year follow-up of children with obstructive sleep apnea.

2022

STUDY OBJECTIVES: Obstructive sleep apnea (OSA) in children is associated with acute metabolic, cardiovascular, and neurocognitive abnormalities. The long-term outcomes of childhood OSA into adulthood have not been established. We performed a 20-year follow-up of patients with polysomnography-documented OSA in childhood compared to a healthy control group to evaluate the long-term anthropometric, sleep, cognitive, and cardiovascular outcomes. METHODS: Children diagnosed with severe OSA between ages 1 and 17 years (mean, 4.87 ± 2.77) were prospectively contacted by telephone as young adults after approximately 20 years. Data collected included reported anthropometric information, educational…

Pulmonary and Respiratory MedicineCOVID-19 children obstructive sleep apnea sleep-disordered breathingAdultSleep Apnea ObstructiveAdolescentPolysomnographysleep-disordered breathingSnoringCOVID-19InfantScientific Investigationsnervous system diseasesrespiratory tract diseasesNeurologychildrenChild PreschoolHumansNeurology (clinical)Childobstructive sleep apneaFollow-Up StudiesJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine
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Sleep Apnea and the Kidney

2020

Abstract Purpose of Review There are some uncertainties about the interactions between obstructive sleep apnea (OSA) and chronic kidney disease (CKD). We critically reviewed recent studies on this topic with a focus on experimental and clinical evidence of bidirectional influences between OSA and CKD, as well as the effects of treatment of either disease. Recent Findings Experimental intermittent hypoxia endangers the kidneys, possibly through activation of inflammatory pathways and increased blood pressure. In humans, severe OSA can independently decrease kidney function. Treatment of OSA by CPAP tends to blunt kidney function decline over time, although its effect may vary. OSA may increa…

Pulmonary and Respiratory Medicinemedicine.medical_specialty030232 urology & nephrologyRenal functionSettore MED/10 - Malattie Dell'Apparato Respiratoriourologic and male genital diseasesKidney transplantation03 medical and health sciences0302 clinical medicineCPAPInternal medicinemedicineSleep-disordered breathingKidneybusiness.industrySleep apneaIntermittent hypoxiamedicine.diseaseCPAP Hemodialysis Kidney transplantation Renal function Sleep-disordered breathingrespiratory tract diseasesObstructive sleep apneaTransplantationmedicine.anatomical_structureBlood pressure030228 respiratory systemNeurologyHemodialysisCardiologyNeurology (clinical)businessRenal functionKidney diseaseCurrent Sleep Medicine Reports
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Cluster Analysis of Home Polygraphic Recordings in Symptomatic Habitually-Snoring Children: A Precision Medicine Perspective

2022

(1) Background: Sleep-disordered breathing (SDB) is a frequent problem in children. Cluster analyses offer the possibility of identifying homogeneous groups within a large clinical database. The application of cluster analysis to anthropometric and polysomnographic measures in snoring children would enable the detection of distinctive clinically-relevant phenotypes; (2) Methods: We retrospectively collected the results of nocturnal home-based cardiorespiratory polygraphic recordings and anthropometric measurements in 326 habitually-snoring otherwise healthy children. K-medoids clustering was applied to standardized respiratory and anthropometric measures, followed by Silhouette-based statis…

children; cluster analysis; obstructive sleep apnea; polygraphy; sleep apnea; sleep-disordered breathing; snoringpolygraphychildrensleep-disordered breathingGeneral Medicinesleep apneaobstructive sleep apneasnoringcluster analysisJournal of Clinical Medicine
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